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From this randomized phase II trial, we included participants from the ribociclib plus letrozole arm

One of DTP cells important immune evasion strategies is the upregulation of immune checkpoint molecules (93)

Ethics approval and consent to participate This study was carried out and approved by the Animal Ethics Committee of the Faculty of Veterinary Medicine at Suez Canal University approved the study design (2019035)

Targeted amino acid and acylcarnitine measurements Targeted amino acid and acylcarnitine measurements were performed using a QTRAP 5500 triple quadrupole mass spectrometer (Sciex, Darmstadt, Germany) coupled to an ExionLC AD (Sciex, Darmstadt, Germany) ultrahigh performance liquid chromatography system

All animal experiments were approved by the Animal Ethics Committee of ShanghaiTech University and conducted in accordance with the standards outlined in the Guide for the Care and Use of Laboratory Animals published by the National Academy of Sciences, USA, and guidelines from the National Institutes of Health

The results are presented in Table 2