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The study showed that the mechanism of action of flavonoid compounds depends on their ability to bind the zinc ion at the active site of the ACE enzyme, thus inhibiting it

Recently, the lipid metabolism-related gene enoyl-CoA-isomerase 2 (ECI2), a mitochondrial enzyme involved in the -oxidation of unsaturated fatty acids, was shown to inhibit neutrophil extracellular trap (NET) formation, thereby blocking CRC development partially through inhibition of lipid synthesis [176]

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Kolbeinsson HM, Chandana S, Wright GP, Chung M

IGF-IR tyrosine kinase interacts with NPM-ALK oncogene to induce survival of T-cell ALK+ anaplastic large-cell lymphoma cells

Case example : A patient receives thromboendarterectomy, with patch graft, carotid artery