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Description

Pathogenic mutations in genes encoding these enzymes result in a long-chain fatty acid oxidation disorder in which the energy homeostasis is compromised and long-chain acylcarnitines accumulate

PK, receptor, prokineticin receptor

Rollin SPG, Lawrence MG, Joshua AM, Selth LA Friend or foe

PMID 27102537

The lack of large, well-controlled RCTs limits the clinical application of oxidative stress modulation in FM

Multiple preclinical and clinical studies showed that epigenetic mechanisms are involved in the pathophysiology and treatment of stress-related depressive and cognitive disorders