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doi: 10.1152/physrev.1979.59.3.527 18

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Preclinical overview of sorafenib, a multikinase inhibitor that targets both Raf and VEGF and PDGF receptor tyrosine kinase signaling

On the contrary, the conventional methods of cancer therapeutics have limited effectiveness, and lack of selectivity

10.1038/nn.2436 Nat

The post-hoc t -test showed a significant difference between groups only in 2W (Figure 4D, *p = 0.0283), although there were no significant differences among the time points