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120 These advanced technologies have mapped the precise spatial zonation of immune responses, revealing how distinct subpopulations of hepatic non-parenchymal cells, such as specific lipid-associated macrophages localized at fibrotic zones or bile ducts, uniquely respond to gut-derived metabolic signals

Given that free cuprous ions catalyse hydroxyl radical formation via the Fenton and HarberWeiss reactions [13, 17], hydrogen peroxide levels were measured in copper-treated cells

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For example, histamine can increase the proliferation of rodent neural stem cells (NSC) or progenitors expressing histamine receptors during both embryonic and postnatal periods and increase the differentiation of adult NSCs into GABAergic neurons and the differentiation of fetal NSCs into glutamatergic FOXP2-positive neurons (Molina-Hernndez and Velasco, 2008