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B12 shots can be especially helpful if you are older, do not eat animal products, have conditions that impact nutrient absorption, or take medications that interfere with nutrient absorption

Benefits of vitamin B12 1

Reported Research Benefits Used in preclinical research focused on obesity, metabolic syndrome, diabetes, aging-related metabolic decline, fat mass reduction, and muscle preservation during caloric deficit

Interestingly, activation of AMPK in the hypothalamus promotes food intake behavior (231)

If you follow a vegetarian or vegan diet, consider fortified foods like plant-based milk and nutritional yeast

B12/MIC is generally well-tolerated and can be safely combined with other treatments like Metformin, NAD+, LDN, and longevity supplements