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T cells within plaques release cellular messengers known as cytokines that regulate inflammatory processes

For a long time these reactions were thought to only have a protein stabilizing structural purpose, but it is now evident that they are also responsible for diverse dynamic functional properties of many enzymes

Wagner, A

In the gastrointestinal tract, tryptophan metabolism proceeds through three main pathways: (1) direct microbial conversion of tryptophan to various aryl hydrocarbon receptor (AhR) ligand molecules, such as indole-3-acetic acid (IAA), indole-3-aldehyde, and indole-3-propionic acid

Duprat R, Wu G-R, De Raedt R, Baeken C

Cyclical vomiting syndrome in children: a population-based study