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Mice across all cohorts consistently ate the provided food regardless of genotype or treatment, resulting in relatively equal nutrient intake

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Milara J, Peir T, Serrano A, Guijarro R, Zaragoz C, Tenor H, Cortijo J (2014) Roflumilast N-oxide inhibits bronchial epithelial to mesenchymal transition induced by cigarette smoke in smokers with COPD

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The FDA's prescribing information includes a warning about transient blood pressure elevation