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Indeed, it has been demonstrated that acetylation plays a key role in the control of CACT function that, together with the long-chain acyl-CoA dehydrogenase, contributes to -oxidation regulation

They were found to have a ruptured chordae tendineae, resulting in lack of coordination (flail) of one of the two leaflets, thereby causing severe backflow of blood through the mitral valve, enlarged left atria and left ventricles, and fluid in their lungs

K.et al (2009)

Akamatsu H, Zouboulis CC, Orfanos CE

Protection of catalpol against triptolide-induced hepatotoxicity by inhibiting excessive autophagy via the PERK-ATF4-CHOP pathway