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The MS/MS resolution was set at 17,500, the AGC target at 5 10 4 , the maximum injection time was 50 ms, isolation window was 2.2 m/z, and dynamic exclusion was 20 s

Mice were treated with IHPC for a total of 14 days, followed by continuous treatment for another 14 days in 13% O 2 hypoxic conditions (Fig

We performed western blotting experiments and confirmed that TST significantly inhibited STAT3 protein expression, and the phosphorylation of STAT3 also decreased accordingly (Fig

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The ratio of absorbance at 260 nm and 280 nm was used to assess the purity of DNA by Thermo Scientific NanoDrop

However, in combination with impaired mitophagy, this process of increased mitochondrial biogenesis may not be sufficient to remove all damaged mitochondria and/or to replace them by newly generated intact mitochondria