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prkn / // Sod2 +/+ and Sod2 // prkn +/+ mice were crossed to generate prkn // Sod2 offspring, which was interbred to produce the desired prkn / // Sod2 (bi-genic) mouse

Inhibition of -Syn Aggregation and Aggregate Reduction Inhibition of -syn aggregation remains an extremely attractive potential target for therapeutic interventions