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2 , CoA The other important product formed in the HMP pathway is NADPH which is useful for metabolic pathways like c holesterol synthesis, steroid and lipid production and fatty acid synthesis

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Consequently, mitochondrial-to-mitochondrial RIRR constitutes a positive feedback mechanism that enhances ROS production, potentially resulting in severe mitochondrial and cellular damage (Fig

Med 389 , 877888 (2023)