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Discussion The export of danger signals through broad-specificity efflux pumps during cellular insults may constitute an early warning system because this process does not rely on extensive cell membrane damage to release danger signals

It is thought to be especially effective against Bacillus dysenteriae, Staphylococcus epidermidis, Staphylococcus aureus, Bacillus subtilis, Escherichia coli, Pseudomonas aeruginosa, Proteus vulgaris and HIV (20, 21, 22, 23)

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Endothelial cells decreased the expression of adhesion molecules, including platelet endothelial cell adhesion molecular-1 (PECAM-1) and intercellular cell adhesion molecular-1 (ICAM-1), when melatonin levels were increased at night [101]

BMC Plant

doi: 10.1038/s12276-022-00752-w 36