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However, evidence is largely based on experiments with exogenously added antioxidants/reducing agents or pro-oxidants

Interventions targeting support for antioxidant defenses, iron homeostasis modulation, or prevention of lipid peroxidation have been shown to attenuate trophoblast dysfunctions caused by ferroptosis

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Under aerobic conditions, pyruvate is usually converted to acetyl CoA and enters the Krebs cycle to produce NADH and FADH2, which are then used in oxidative phosphorylation to generate adenosine triphosphate (ATP)