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38,39 This study characterized antimicrobial metabolites from Burkholderia stagnalis , a rhizobacterium with genomic potential for diverse secondary metabolites

The first 50 principal components were used to cluster the cells based on the shared nearest neighbours (SNN) algorithm and visualised in two dimensions by uniform manifold approximation and projection (UMAP)

Such pathophysiological features are hallmarks of conditions that are targets for neuronal transplantation interventions, namely TBI, SCI, stroke, and localized basal ganglia neurodegeneration (HD and PD)

Both families of enzymes use NADP + as cofactors to perform reversible reactions, where isocitrate is oxidatively decarboxylated to alpha-ketoglutarate and generates one NADPH per reaction

Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of alpha-Ketoglutarate-Dependent dioxygenases

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