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Description

The largest organ of the immune system is the spleen, whose main function is the production of antibodies, lymphocytes, and monocytes

N.ElwakeelA.DhanjalJ

Many tumor types, including lung, liver, and head and neck carcinomas, harbor mutations in KEAP1 or NRF2 that lead to sustained Nrf2 activity

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Challenges in therapeutic translation Targeting specificity & off-target toxicity A major challenge is achieving cardiomyocyte-specific ferroptosis modulation without harming other cells