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An additional mechanism of ERK activation by peroxynitrite, relying on a direct interaction with a calcium-dependent PKC isoform, has also been reported in rat-1 fibroblasts (57)

10.3390/healthcare12171721 282 LiuJ.WangF

For instance, telomerase inhibitor triethylenetetramine (TETA) in the treatment of breast cancer [122], glycolysis inhibitor 3-(3-Pyridinyl)-1-(4-pyridinyl)-2-propen-1-one (3-PO) in NSCLC cells [194], respiratory chain complex I inhibitor metformin, ATP synthase inhibitor oligomycin A and Bcl-2 inhibitor venetoclax in CLL patient-derived cells [104]

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