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The increase in lactate that we detected points towards a defect in oxidative energy metabolism, but this conclusion must be treated cautiously given the difficulty of measuring lactate in the presence of the much larger and broader macromolecule (MM) resonance at ~1.35 ppm, with the lactate signal being a small shoulder on that peak (Fig

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Quality of life and functional movements were also evaluated

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doi: 10.1111/ejn.v53.12 52 ReayWRCairnsMJ

202 However, after the end of treatment with diazoxide and alkylating agents, tumors in this group grew faster than in controls