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Glyoxalase-1-dependent methylglyoxal depletion sustains PD-L1 expression in metastatic prostate cancer cells: A novel mechanism in cancer immunosurveillance escape and a potential novel target to overcome PD-L1 blockade resistance

190,191 The C-terminus of MDM2 is crucial for export of wild-type p53 from the nucleus to the cytoplasm, where it is degraded via E3 ubiquitin ligases

The cell viability was evaluated by MTT assay, and the 50% cytotoxicity concentration (CC 50 ) of allium glycosides was 65.33 5.272 M, while that of mitifosine was 20.39 1.69 M

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Skin-lightening soaps can be safe if dermatologically tested and used as directed

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