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Li Y, Zhong H, Wu M, Tan B, Zhao L, Yi Q, et al

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RIG-I, Retinoic Acid-Inducible Gene I

In a sciatic nerve IRI model, oral administration of lutein before ischemia and after reperfusion reduced neuropathic pain and nerve injury by decreasing oxidative stress and suppressing inflammatory mediators, such as NF- B and TNF- , while preserving endogenous antioxidant defenses [56]

This therapy can be beneficial for patients who are unable to obtain sufficient amounts of this nutrient through dietary sources or oral supplements

GSH/Cr ratio