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doi: 10.1016/B978-0-12-802168-2.00038-5 173 FloheLGnzlerWASchockHH

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Furthermore, 3-mercaptopyruvate sulfurtransferase-derived mitochondrial H2S may play a regulatory role in BCAA catabolism and mediate critical cardiovascular protection in heart failure (74)

Deficiencies can impair fat metabolism and increase homocysteine, a marker linked to liver damage

Here we show that SIRT3, a mitochondrial deacetylase highly expressed in HSCs but reduced during aging, suppresses the HSC response to aging that drives maladaptive trained immunity, chronic inflammation and tissue functional decline in mice

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