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These ingredients can be used as alternative candidates for drug development to alleviate AMRs and adverse drug reactions

10.1186/s13063-024-08187-6 75 RenX.ZouL.ZhangX.BrancoV.WangJ.CarvalhoC.et al (2017)

You can react more easily to topical products that were previously fine and have a response to environmental triggers [like heat and cold], says Robyn Gmyrek, M.D., board-certified dermatologist at UnionDerm in New York City