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This disruption in the skins barrier function also leads to the breakdown of collagen and elastin, which are crucial for maintaining a youthful, plump complexion

Given that aging is associated with a decline of mitochondrial functions along with the development of aging-related diseases, and given that the tissue and circulating levels of MOTS-c fall with age, it is compelling to hypothesize that declining MDP levels are also related to age-related metabolic deterioration