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2.3 Network pharmacology: a revolutionary tool in Alzheimers disease research Network pharmacology is a systems-based approach that integrates bioinformatics, cheminformatics, and systems biology to investigate the complex interactions between drugs, targets, and diseases

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Many of the eicosanoids contractile effects on smooth muscle can be inhibited by lowering extracellular calcium or by using calcium channel-blocking drugs

For example, NAT10 regulates fatty acid metabolism and redox balance through ACOT7 or FSP1, where the generation of lipid peroxidation products (e.g., MDA) not only marks ferroptosis but may also activate the inflammasome and promote pyroptosis [226, 322]