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This breadth of action distinguishes it from growth factors with a narrow receptor focus and helps explain experimentally observed tissue protection across different organ systems

I mean, this becomes medical to me

The Role of Neurosteroids in Memory Deficits Associated With Stress and Anxiety Disorders Three large scale major neural networksthe default mode network, central executive network, and salience networkcontribute to cognitive processing within the human brain and function together to facilitate adaptive responses of the CNS (286)

This may lead to autophosphorylation of a bidentate docking site in the carboxy-terminal cytoplasmic tail (tyrosine residues Tyr1349 and Tyr1356)

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After loading the supernatant, the column was washed with 20 column volumes of 90% buffer A (0.5 M NaCl, 0.2 M sodium phosphate, and 20 mM imidazole) and 10% buffer B (0.5 M NaCl, 0.2 M sodium phosphate, and 0.5 M imidazole) followed by elution with 100% buffer B