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In contrast, GDNF mimetics and blood-brain barrier-penetrating CDNF peptides offer the advantages of both targeting and delivery efficiency, with preliminary preclinical or clinical data accumulated, providing a more translationally promising solution to the delivery challenges of NTFs-based therapies

Challenges of modeling intrinsic bacterial defenses against PMN-derived ROS It is important to note that the chemistry of oxidants in the neutrophil phagosome is far different from that of the cell's surroundings or that of dilute solutions to which oxidants have been added

47,49 Exercise-induced physiological cardiac growth exhibits increased proliferation markers in cardiomyocytes such as EdU, Ki67, and phosphorylated histone H3 (pHH3)

MTF2 from WT mESCs was eluted as a broad peak, likely corresponding to a mixture of the monomeric and dimeric forms of MTF2-containing PRC2.1 (Fig

YdpA mutant, which had lower levels of BSH and higher levels of BSSB, had reduced survival in human neutrophils [82]

Soh J, Kawauchi A, Kanemitsu N, Naya Y, Ochiai A, Naitoh Y, et al