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To inform the development of updated WHO guidelines and expanded treatment criteria, we conducted a systematic review and meta-analysis and provided summary estimates of the efficacy of antiviral therapy in groups stratified by baseline VL ( 18 years and 13 (31%) in those 20,000 IU/mL

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Arginine is found to regulate glycolysis and mitochondrial oxidation, and exogenous addition of arginine can induce a metabolic transition from glycolysis to OXPHOS

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Clonal abundance of tumor-specific CD4(+) T cells potentiates efficacy and alters susceptibility to exhaustion