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No correction is made for differences in the bioavailability of crystalline B12 from supplements or fortified foods compared with B12 from food because the absorption differences between these two B12 sources are assumed to be small

This understanding fueled the development of infant formula until research stumbled over surprising findings

Research cited by Gameday Mens Health found that oral vitamin B12 absorption was limited to just 50% at low dosages and only 1% at higher dosages, while injected B12 reaches the bloodstream at nearly 100% bioavailability

According to research published in the Indian Journal of Endocrinology & Metabolism, vitamin B12 deficiency affects 47% of adults, especially older adults, vegetarians, and people with digestive issues

The benefit comes from replacing whats missing, not from extra B12 on top of normal levels