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Cells were treated with various concentrations of GSSSG (25200 M) or LPS (10 g/mL) for 6 h, and then living cells were detected using Calcein-AM

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In the process, proteases remove the C-terminal globular domain

Marine peptides The exceptional biodiversity of marine macro- and microorganisms has established oceans as a key source of bioactive molecules, with marine-derived peptides demonstrating unique structural characteristics and diverse bioactive functions such as enhanced bioavailability, reduced toxicity, and greater biocompatibility compared to terrestrial counterparts

184 In gastric cancer, serum factors IL-6 and IL-8 can stimulate CD45 + CD33 low CD11b dim MDSCs to express ARG1 and ultimately inhibit CD8 + T cell function through the PI3K-AKT signaling pathway (Fig