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In our study, rats treated with AZM alone exhibited weight loss and reduced liver weight, indicative of systemic toxicity and metabolic disruption

Lactate was found to target MAS-associated G protein-coupled receptor X2 (MRGPRX2) expressed by mast cells to inhibit both the early (calcium mobilization and degranulation) and late (chemokine/cytokine release) phases of mast cell activation in asthma 135

The human research is early but the preclinical literature is deep and consistent

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And do they work better raw or cooked