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An interesting study demonstrated that Nrf2 has detrimental effects on the heart by promoting ferroptosis during myocardial autophagy deficiency (100)

Beyond classical antioxidant enzymes, dysregulation of multiple OS-related proteins and pathways has been reported in MS, including peroxiredoxin (PRX), an enzyme critical for reducing H 2 O 2 whose dysregulation may impair the cellular ability to handle peroxides (Voigt et al., 2017

On the other hand, salicylic acid (SA)-deficient NahG plants display enhanced susceptibility to viral infections

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Stimulates and maintains appetite

[DOI] [Google Scholar] 48.Beitzke B., Pate D.W