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Possible reasons could be that (1) DAB is preferred by LaccID over other aromatic substrates, and (2) DAB labeling was performed in sodium cacodylate buffer, which does not contain laccase inhibitors such as halides and thiols

Modern DDSsincluding lipid-based, polymeric, and stimuli-responsive platformshave demonstrated superiority over conventional therapies by optimizing pharmacokinetics, minimizing off-target effects, and enabling targeted delivery to pathological sites (e.g., renal tubules and inflamed joints)

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