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Baicalein inhibits cerebral ischemia-reperfusion injury through SIRT6-mediated FOXA2 deacetylation to promote SLC7A11 expression

HA and IR can exacerbate endothelial damage and disrupt endothelium-dependent vasodilation mechanisms, leading to vascular smooth muscle hypertrophy and lipid metabolism disorders (Krentowska and Kowalska, 2022