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Although intravenous glutathione delivers a much higher therapeutic dose that enhances its efficacy, it also provides a narrower margin of safety due to the possibility of overdose toxicity

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This outdated practice offers no benefit for this administration route and only increases tissue trauma

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Glutathione benefits include the ability to help reduce the appearance of dark spots, age spots, and melasma by inhibiting the enzyme tyrosinase, which is involved in melanin production

Deficiency of GSH, the major intracellular thiol, has been shown in human patients with acute pancreatitis, HIV infection, hyperthyroidism, Type I diabetes, and cirrhosis, 3-6 and has been associated with disease severity and decreased survival in some studies