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10.1038/35079100 113 SatohJ.YagihashiS.ToyotaT

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Smit JW, Basile P, Prato MK, Detalle L, Mathy F-X, Schmidt A, et al

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In MDS patients, hepatocyte mitochondrial DNA depletion leads to ROS accumulation, which drives lysosomal ferritin degradation and iron release, triggering a lipid peroxidation-ferroptosis cascade [156]