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Strong support exists for hydration and correction of deficiencies such as iron or B12

Sequence: Gly-His-Lys, with high-affinity Cu(II) binding Plasma levels fall from ~200 ng/mL at age 20 to ~80 ng/mL at 60 Modulates expression of ~4,000 human genes (Pickart et al., 2012) Active in wound-healing, fibroblast proliferation and antioxidant defence assays Sequence H-Gly-His-Lys-OH (Cu complex) Molecular weight 340.39 g/mol (free tripeptide)

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Anti-Aging Effects Sustained release of growth hormone has a crucial role in improved skin elasticity, reduced wrinkles, and enhanced collagen production, generally contributing to a more youthful appearance

We stratified analyses by era (19972001, 20022006, 20072011, 20122016, and 20172021)

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