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In a Chinese phase II clinical trial, mazdutide decreased HbA1c by 1.41% to 1.67% in a dose-dependent manner, while a placebo decreased HbA1c by + 0.03% [102]

7.5 Precision microbiomics and emerging approaches The integration of high-throughput sequencing, multi-omics platforms, and artificial intelligence offers new opportunities for the precise characterization of host-specific microbiota and microbehost interactions (Ratiner et al., 2024