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While this may be true for the terminal phase of WD in which massive copper overload causes liver failure, an increasing body of evidence demonstrates that such uncontrolled Fenton chemistry reactions do not drive disease pathogenesis

The identified species-specific metabolites also suggest that caution should be exercised when extrapolating animal experimental data to humans, providing valuable references for future translational research

doi: 10.1038/srep04173 97 KatayamaN.YamamoriS.FukayaM.KobayashiS.WatanabeM.TakahashiM.et al

When it comes to retinol, it's important to note what purging looks like compared to breaking out

Conversely, -syn dysregulates iron homeostasis: it exhibits ferrireductase activity, reducing Fe 3+ to Fe 2+ and elevating labile iron levels, while its overexpression redistributes iron to perinuclear inclusions

doi: 10.1002/jmri.24478, 13 EmirU