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CRISPR/Cas9-mediated knockout of Lcn2 in human breast cancer cell line MDA-MB-231 ameliorates erastin-mediated ferroptosis and increases cisplatin vulnerability

this special approach of compatibility has achieved the effect of enhancing the curative effect and reducing the toxic and side-effects, for example, with the use of drugs such as ligustrazine hydrochloride injection, tranquilizing and antiepileptic prescription, wild jujube seed decoction, and gastrodin injection

doi: 10.3233/JAD-160926 132

Heneka et al., 2025)

Purpose: Analytical methods are required for assessing the quality of GSH drug substance and drug product as a part of FDAs evaluation

Early sterol biosynthesis genes, such as the steroid reductase DET2, were up-regulated in SL compared with galls (Fig