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doi: 10.1093/biolre/ioab066 117 LiDKZhouZMiaoMHeYWangJFerberJet al

PGE2 produced by MDSCs can elevate PD-L1 expression in both intratumoral MDSCs and TAMs, contributing to the differentiation of IL-10-producing T cells into dysfunctional, and exhausted T cells [38]