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However, the recovery of the cell growth by overexpression of SHM2 and/or CYS4 in GCI/ SERs seemed to be the result that surplus biosynthesized l-Ser was metabolizing to Gly and l-Cys (Fig

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Karaa M, Kili E, Yazici B, Demir S, Torre J de la

Li R, Zan Y, Sui K, Zhu S

Ismail, A., Abdelghany, A

Effective half-life (t 1/2eff ) has been proposed as a clinically relevant pharmacokinetic parameter for drug formulations that exhibit complex drug release and absorption, including extended-release formulations and drugs with multicompartment pharmacokinetics