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These pathways could also affect cancer growth, he says

194 They are essentially protein precursors with a conserved amino-terminal (N-terminal) signal peptide domain, an antimicrobial C-terminal domain mature peptide, and a cathelin-like domain

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[2] Causes are usually related to conditions that give rise to malabsorption of vitamin B 12 , particularly autoimmune gastritis in pernicious anemia

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doi:10.1177/1747493019876538 Harris WS, Del Gobbo L, Tintle NL