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Acknowledgments The main figures were assembled using BioRender ( The authors would like to acknowledge the support provided from their parent institution

However, human safety data beyond 12 weeks does not yet exist long-term tolerability remains unknown

Permeating cryoprotectants Dimethyl sulfoxide is one of the most widely used CPAs due to its ability to penetrate cell membranes and reduce ice crystal formation by lowering the freezing point of water (Friedler et al