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Notably, apoptosis is triggered in response to DNA damage resulting in nuclear p53 activation and consequent upregulation of pro-apoptotic proteins and their translocation to mitochondria to trigger the MOMP-mediated pathway

we do not recommend its use with the Click-iT detection reagents

Borkent, J., Ioannou, M., Laman, J

Zileuton, an FDA-approved oral medication for treating asthma, is an ALOX5 inhibitor that exerts neuroprotective effects by blocking ALOX5-mediated glutamate toxicity and ferroptosis in HT22 cells, a mouse hippocampal cell line [301]

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

Available online at: 41 GgotekA.SkrzydlewskaE