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The conjugate also sensitized GBM cells to TMZ treatment, increasing the toxicity by a further two-fold, despite rucaparib showing no evidence of synergism with TMZ

Mitochondrial cytochrome P450 enzymes, embedded in the IMM with most of their protein body facing the matrix, bind a single heme moiety 88,89

Emerging trends show that graphene-based nanomaterials develop unique properties and can be employed for biomedical applications, particularly in drug delivery and tissue engineering (Goenka et al., 2014)

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Vitamin C A potent antioxidant, vitamin C is essential for immune system support and fighting oxidative stress

This scoring system allowed for semi-quantitative evaluation of cartilage integrity based on macroscopic features such as softening, fibrillation, erosion, ulceration, and complete cartilage loss [1]