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The RNA expression level of GSTP1 was detected with the use of ABI PRISM 7500 Fast Real-Time PCR System (Thermo Fisher Scientific)

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5 Discussion and perspectives In recent years, in OA, a complex degenerative joint disease, increasing research indicates that ferroptosis not only exists in the pathological process but is also closely related to pathological features such as articular cartilage degeneration, synovial inflammation, and subchondral bone changes