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In addition, both preclinical and clinical literature often underrepresent females, limiting insights into sex-specific immunometabolic and hormonal modulators of treatment response (Seyedinia et al., 2023

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Ferroptosis in erythropoiesis Several studies have investigated the occurrence of ferroptosis in bone marrow precursors of erythrocytes and explored the role of this RCD in hematopoiesis in general and specifically in erythropoiesis (Fig

Chlorogenic acid rich in coffee pulp extract suppresses inflammatory status by inhibiting the p38, MAPK, and NF-B pathways

Anastasiou D, Poulogiannis G, Asara JM, Boxer MB et al (2011) Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses

Recent data indicates that anthocyanins provide health benefits partially through their interaction with gut microbiota [125], influencing the microbial environment of the gastrointestinal tract (via their metabolism into bioactive substances) or by modifying the prevalence of specific microbial populations [126, 127]