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X-tremeGENE HP DNA Transfection Reagent (Roche) was used for transient transfection, and the total amount of transfected DNA was normalized by addition of empty control plasmids

In contrast, FHOD3 is implicated in sarcomere assembly and maintenance (Fujimoto et al., 2016

doi: 10.1186/1471-2164-15-466 52 MaZ.ZhangY.WuL.ZhangG.SunZ.LiZ.et al

These effects can be effectively counteracted by treatment with the KCNN3 channel inhibitor edelfosine and the calcium chelators BAPTA-AM, suggesting a promising therapeutic strategy for HCC patients