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Because of the biological and pathological differences between hematologic malignancies and solid tumors, DNMT inhibitors demonstrated promising results in hematological malignancies, but not in solid tumors (17)

Furthermore, the functional enrichment analyses indicated that the differentially expressed genes (DEGs) between the mild and severe groups were significantly related to redox homeostasis (GO:0045454, GO:0006979, hsa05208, R-HSA-9818027, and R-HSA-3299685), cytokine signaling (GO:0034097, R-HSA-1280215, and R-HAS-449147), ferroptosis (hsa04216), and ferroptosis-related pathways (hsa04390 and hsa04310) (Fig

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