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They may even disrupt both pyruvate and succinate oxidation pathways

DehghaniSAlipoorESalimzadehAYaseriMHosseiniMFeinle-BissetCet alThe effect of a garlic supplement on the pro-inflammatory adipocytokines, resistin and tumor necrosis factor-alpha, and on pain severity, in overweight or obese women with knee osteoarthritis

Interfaces 7 , 1302913037 (2015)

Abstract Sororin is essential for establishing sister chromatid cohesion concurrently with DNA replication in metazoans

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In summary, this review has identified several natural productssuch as Withania somnifera , Ocimum sanctum , curcumin, and Astragalus membranaceus that have demonstrated significant effects on thyroid function or pathology in preclinical models, with some like Astragalus and Dioscorea nipponica showing promise in preliminary clinical studies